Delaminomycins, novel extracellular matrix receptor antagonists. V. Biosynthesis.
نویسندگان
چکیده
منابع مشابه
Delaminomycins, novel extracellular matrix receptor antagonist. III. Physico-chemical properties and structure elucidation of delaminomycins B and C.
delaminomycin A (1, Fig. 1), a novel compound possessing an acyl tetramic acid moiety1}, has been isolated from the culture broth of Streptomyces albulus MJ202-72F3 which was deposited in the Fermentation Research Institute of the Agency of Industrial Science and Technology, Japan, with the accession No. FERMP-126742). The strain also produced some compounds related to delaminomycin A as minor ...
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In order to develop a new class of immunomodulator we have searched for a low molecular weight inhibitors of cell adhesion to components of extracellular matrix (ECM), fibronectin (FN), laminin (LM) and collagen type IV (CL), and succeeded to find a group of novel antibiotics, named delaminomycins. Delaminomycins were isolated from the mycelium and cultured broth of Streptomyces albulus MJ202-7...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1993
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.46.1390